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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKI67 All Species: 7.88
Human Site: T2113 Identified Species: 24.76
UniProt: P46013 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46013 NP_001139438.1 3256 358694 T2113 P P P E S M D T P T S T R R R
Chimpanzee Pan troglodytes XP_508147 3257 358658 T2114 P P P E S M D T P T S T R R R
Rhesus Macaque Macaca mulatta XP_001089669 2126 233775 A1103 A R S L E D L A G F K E L F Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_001074586 3177 350846 T1363 S Q A E P V K T P A S T K R L
Rat Rattus norvegicus XP_225460 3119 343332 R2089 F I S P Q P G R P V R T Q N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421822 2556 283606 S1533 R K T V H P A S I K Q T E K D
Frog Xenopus laevis NP_001128553 2510 270869 L1487 T N N G E V S L Q I D S E T G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782273 1825 188999 A797 P K A A T P K A A T P K A A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 55.1 N.A. N.A. 43.1 43.1 N.A. N.A. 22.4 21.7 N.A. N.A. N.A. N.A. N.A. 24.1
Protein Similarity: 100 98.7 57.3 N.A. N.A. 58.2 57 N.A. N.A. 38.5 38.1 N.A. N.A. N.A. N.A. N.A. 34.9
P-Site Identity: 100 100 0 N.A. N.A. 40 13.3 N.A. N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 6.6 N.A. N.A. 53.3 20 N.A. N.A. 20 13.3 N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 25 13 0 0 13 25 13 13 0 0 13 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 25 0 0 0 13 0 0 0 13 % D
% Glu: 0 0 0 38 25 0 0 0 0 0 0 13 25 0 0 % E
% Phe: 13 0 0 0 0 0 0 0 0 13 0 0 0 13 0 % F
% Gly: 0 0 0 13 0 0 13 0 13 0 0 0 0 0 13 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 0 0 0 0 13 13 0 0 0 0 0 % I
% Lys: 0 25 0 0 0 0 25 0 0 13 13 13 13 13 0 % K
% Leu: 0 0 0 13 0 0 13 13 0 0 0 0 13 0 13 % L
% Met: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 13 0 0 0 0 0 0 0 0 0 0 13 13 % N
% Pro: 38 25 25 13 13 38 0 0 50 0 13 0 0 0 0 % P
% Gln: 0 13 0 0 13 0 0 0 13 0 13 0 13 0 13 % Q
% Arg: 13 13 0 0 0 0 0 13 0 0 13 0 25 38 25 % R
% Ser: 13 0 25 0 25 0 13 13 0 0 38 13 0 0 0 % S
% Thr: 13 0 13 0 13 0 0 38 0 38 0 63 0 13 13 % T
% Val: 0 0 0 13 0 25 0 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _